Introduction of Chemometric 7.5 hp- Models-DOE

Introduction of Chemometric 7.5 hp- Models-DOE

10/4/2010 7.5p Introduction H. Antti modified 

2010 A. Linusson

The information aspect in the study of complex systems

 Study Design (Design of Experiments (DOE))

 Sample Selection (DOE and MVA Design)

 Sample Preparation (Development of Protocols)

 Analytical Characterization (Development of Protocols)

 Generation of Representative Data (Methods)

 Data Evaluation (Methods, Models and Prediction)

 Validation (Methods)

Chemometrics is a concept not a statistical method!

The development of analytical instrumentation .....

The post-genomic explosion – genomics, proteomics, 

metabonomics ......

Increased computer capacity .......

.....have simplified the collection of huge amounts of data.

In order to analyse these complex multivariate systems 

efficient, reliable and robust statistical methods are needed 

(experimental design & multivariate analysis).

The need to variate analysis of multivariate data is that to avoid risk for random correlations.

For example: