MEKC(Micellar Electrokinetic Chromatography)

Micellar

Requiremens: favorable kinetic properties (efficiency), separate peaks in chromatogram (peak capacity), adequate selectivity, and short separation time.

The selectivity is affected by the surfactant and the addition of complexing agents and/or organic solvents to the buffer.

Surfactants such as Sodium dodecyl Sulfate is important because it favor the kinetic properties.

After optimizing surfactants, addictives should be made into use for further optimization