Applied NMR Spectroscopy, 7.5 ECTS

About the course

The course aims to provide an understanding of how the chemical structures and dynamics of organic molecules can be studied by NMR spectroscopy. Fundamental theory of nuclear spin resonance is presented and the concepts of chemical shift, J-coupling, relaxation and the nuclear Overhauser effect (NOE) are discussed. Vector models are used throughout the course as a tool for analysing the different sequencies of pulses employed in common NMR techniques. Emphasis is given to applications and practical exercises, both computer-based and instrumental. In particular, experimental work is directed to the collection and interpretation of data and the analysis of different procedures for determining the structures of organic molecules, and includes one-dimensional 1H- och 13C-methods as well as 2-dimensional experiments such as COSY, TOCSY and heteronuclear measurements. The course concludes with a project in which the student examines the structure of an organic compound using the methods and interpretation procedures covered in the course.

Level of Education: Advanced

Literature

Horst Friebolin
Basic One- and Two-dimensional NMR Spectroscopy.
Wiley VCH Publisha :
ISBN: 3-527-29513-5 

Introduction and basic concepts
The lectures about NMR